Exploring the use of Plant-Based Nanoparticles for Drug Delivery: Challenges and Opportunities

Abstract

The use of plant-based nanoparticles [PBNs] for drug delivery has gained significant attention in recent years due to their biocompatibility, ecofriendliness, and potential therapeutic efficacy. PBNs offer several advantages over conventional synthetic nanoparticles, such as reduced toxicity, lower immunogenicity, and better patient acceptance. This paper explores the opportunities and challenges associated with utilizing plantbased nanoparticles in drug delivery systems. Key opportunities include their ability to enhance the bioavailability of drugs, targeted delivery, and potential for use in personalized medicine. However, challenges such as scalability, regulatory hurdles, and variability in plant composition need to be addressed. The paper also discusses recent advancements in the development of plant-based nanocarriers, including their preparation methods, functionalization, and the types of drugs that can be delivered effectively. A comprehensive understanding of the mechanisms of action, safety profiles, and long-term effects of PBNs is crucial for their successful integration into clinical settings.