Review Article on Investigating the Antibacterial, Antifungal and Antiviral Efficacy of Andrographis Paniculata and Azadirachta Indica Extract Used in Traditional Indian Medicine

Abstract

This review highlights the need for additional analytical research to find novel drugs while attempting to summarize the plant's antibacterial and antifungal qualities. There is no denying the importance of natural ingredients in pharmaceuticals. From this perspective, Azadirachta indica is emerging as the cynosure of contemporary medicine. This plant has historically been widely used to treat a wide range of illnesses in both the plant and animal kingdoms. The pharmacological properties of neem plants have been linked to a variety of compounds. Aspergillus flavus, Alternaria solani, and Cladosporium were the three fungal species against which Azadirachta indica (neem) leaf extract was tested for antifungal activity. Ethanolic and methanolic extracts at different concentrations (25%, 50%, 75%, and 100%) were produced and tested against test organisms using disc diffusion. An antioxidant is a chemical that can stop the chain events that harm cells by eliminating free radical intermediates. It can also prevent other oxidation reactions by lowering the stress that causes many degenerative diseases. The versatile tropical herb Andrographis paniculata Nees is said to have numerous therapeutic benefits. This study aimed to assess the antioxidant activity of Andrographis paniculata Nees extracts in hexane, DCM, and methanol in vitro. The toxicity and antifungal properties of neem extract were compared using ketoconazole